MYL2 Antibody
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Description
Product Specs
Product Science Overview
Myosin Light Chain 2 (MLC-2) is a crucial component of the myosin complex, which plays a significant role in muscle contraction. The antibody “Mouse Anti Human Myosin Light Chain 2” is specifically designed to target and bind to the MLC-2 protein in human samples. This antibody is widely used in various research applications, including immunoprecipitation (IP), western blotting (WB), and immunohistochemistry (IHC).
Myosin is a motor protein that interacts with actin filaments to generate force and movement in muscle cells. It is composed of two heavy chains and four light chains. The light chains are further divided into essential light chains (ELC) and regulatory light chains (RLC). MLC-2 is one of the regulatory light chains and is essential for the proper functioning of the myosin motor protein.
In the heart, there are two isoforms of MLC-2: MLC-2a and MLC-2v. MLC-2a is predominantly expressed in atrial muscle, while MLC-2v is found in ventricular muscle . The expression of MLC-2 is crucial for the development and differentiation of cardiac muscle cells.
The “Mouse Anti Human Myosin Light Chain 2” antibody is a monoclonal antibody produced in mice and is specific to the human MLC-2 protein. This antibody is used in various research applications to study the expression and function of MLC-2 in human tissues.
Applications
- Immunoprecipitation (IP): This technique allows for the isolation and concentration of a specific protein from a complex mixture using an antibody that specifically binds to that protein.
- Western Blotting (WB): This method is used to detect specific proteins in a sample by separating them based on their size using gel electrophoresis and then transferring them to a membrane where they are probed with antibodies.
- Immunohistochemistry (IHC): This technique involves the staining of tissue sections with antibodies to visualize the distribution and localization of specific proteins within the tissue.
Reactivity
The Mouse Anti Human Myosin Light Chain 2 antibody is known to react with human, mouse, and rat samples . This broad reactivity makes it a valuable tool for comparative studies across different species.
The study of MLC-2 and its role in muscle contraction and cardiac function is critical for understanding various muscle-related diseases and conditions. The Mouse Anti Human Myosin Light Chain 2 antibody provides researchers with a reliable tool to investigate the expression and function of MLC-2 in different tissues and under various physiological and pathological conditions.
