Lypressin

Lypressin
Cat. No.
BT16809
Source
Synonyms
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity

Greater than 99.0% as determined by RP-HPLC.

Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipped with Ice Packs
In Stock

Description

Lypressin is a hormone used to prevent or control the frequent urination, increased thirst, and loss of water associated with diabetes insipidus (water diabetes). Its molecular weight is 1056.2 Dalton having an amino acid sequence of Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2. The Molecular Formula is: C46H65N13O12S2.
The CAS Number is: 50-57-7.

Product Specs

Description
Lypressin is a hormone utilized to prevent or manage frequent urination, increased thirst, and water loss associated with diabetes insipidus (water diabetes). It possesses a molecular weight of 1056.2 Daltons and an amino acid sequence of Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2. Its molecular formula is C46H65N13O12S2, and its CAS number is 50-57-7.
Physical Appearance
Sterile Filtered White lyophilized powder.
Formulation
The protein (1mg/ml) has undergone lyophilization without any additives.
Solubility
It is advised to reconstitute the lyophilized Lypressin in sterile 18MΩ-cm H2O at a concentration not less than 100 μg/ml. This solution can be further diluted in other aqueous solutions. Lypressin also exhibits solubility in a 1% Acetic Acid solution.
Stability
Store lyophilized Lypressin between 2-8°C, avoid freezing. Upon reconstitution, Lypressin should be stored at 4°C for a period of 2-7 days. For future use, store below -18°C. Prevent freeze-thaw cycles.
Purity
Greater than 99.0% as determined by RP-HPLC.

Product Science Overview

Chemical Structure and Properties

Lypressin has the chemical formula C46H65N13O12S2 and a molecular weight of 1056.23 g/mol . It belongs to the class of organic compounds known as oligopeptides, which are sequences of between three and ten alpha-amino acids joined by peptide bonds .

Mechanism of Action

Lypressin acts on the vasopressin receptors in the body, specifically the V1a, V1b, and V2 receptors . These receptors are involved in various physiological processes, including the regulation of water balance, blood pressure, and vascular tone .

Medical Uses

Lypressin is primarily used to treat central diabetes insipidus, a condition characterized by excessive thirst and urination due to a deficiency of vasopressin . It is also used to improve vasomotor tone and blood pressure in certain medical conditions .

Pharmacokinetics

The pharmacokinetics of lypressin, including its absorption, distribution, metabolism, and elimination, are not well-documented . However, it is known to have vasoconstricting activities, which can be enhanced when combined with certain other drugs .

Adverse Effects and Interactions

Lypressin can interact with various medications, potentially increasing the risk or severity of adverse effects such as hypertension . It is important to use this medication under the guidance of a healthcare provider to avoid life-threatening adverse events .

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