LY6D Human

The LY6D gene is located on chromosome 8 in humans and encodes a protein that is primarily found on the cell surface. The protein is characterized by its involvement in the differentiation of lymphocytes, particularly in the early stages of B-cell and T-cell development. LY6D acts as a specification marker at the earliest stage of lymphocyte differentiation, marking the transition between B-cell and T-cell lineages .

LY6D is involved in several biological pathways, including the metabolism of proteins and B-cell development pathways. It is predicted to be active in the extracellular region and plasma membrane, where it plays a role in cell surface interactions and signaling . The protein is also associated with various diseases, such as squamous cell carcinoma of the head and neck, and scrotum Paget’s disease .

Recombinant LY6D refers to the LY6D protein that has been produced through recombinant DNA technology. This involves inserting the LY6D gene into a suitable expression system, such as bacteria or mammalian cells, to produce the protein in large quantities. Recombinant LY6D is used in various research applications, including the study of its role in immune response and its potential as a therapeutic target.

LY6D has been studied extensively for its role in the immune system and its potential implications in cancer research. For instance, it has been identified as a marker for certain types of cancer, including squamous cell carcinoma and nasal cell carcinoma with sebaceous differentiation . Additionally, LY6D is used in various assays and experimental setups to study its function and interactions with other proteins.