KRT23 Antibody

Cytokeratins are a group of intermediate filament proteins found in the intracytoplasmic cytoskeleton of epithelial tissues . They play a crucial role in providing structural support to cells, helping them resist mechanical stress . Cytokeratins are categorized into two types: acidic type I and basic or neutral type II . These proteins are expressed in a tissue-specific manner, making them valuable markers for identifying the cell of origin in various human tumors .

Cytokeratin 23 (CK23) is one of the lesser-known members of the cytokeratin family. Like other cytokeratins, CK23 is involved in maintaining the structural integrity of epithelial cells. The specific expression pattern of CK23 in different tissues and its role in various physiological and pathological processes are still under investigation. However, it is known that cytokeratins, including CK23, are commonly used as markers in the diagnosis and classification of epithelial tumors .

Mouse anti-human antibodies are secondary antibodies generated by immunizing mice with human antigens. These antibodies are then harvested and purified for use in various immunological assays . Mouse anti-human antibodies are widely used in research and diagnostic applications due to their high specificity and affinity for human antigens . They are commonly used in techniques such as immunohistochemistry (IHC), enzyme-linked immunosorbent assay (ELISA), and Western blotting .

The combination of mouse anti-human antibodies with cytokeratin 23 is particularly useful in the field of cancer research and diagnostics. By targeting CK23, researchers can identify and study the expression patterns of this protein in various epithelial tissues and tumors. This can provide valuable insights into the role of CK23 in cancer development and progression, as well as its potential as a diagnostic marker .