Isochorismatase Domain Containing 2 (ISOC2) is a protein-coding gene that encodes a protein known as Isochorismatase Domain-Containing Protein 2. This protein is involved in various cellular processes, including protein destabilization. The ISOC2 gene is located in the cytoplasm and nucleus of human cells .
The ISOC2 gene is a member of the isochorismatase family and has several aliases, including FLJ23469 and Isochorismatase Domain-Containing Protein 2, Mitochondrial . The gene is located on chromosome 19 and has been assigned the HGNC (HUGO Gene Nomenclature Committee) ID 26278 .
The protein encoded by the ISOC2 gene consists of 205 amino acids and has a molecular weight of approximately 23 kDa . It is expressed in various tissues and has been studied for its role in protein destabilization and other cellular functions .
Recombinant human ISOC2 protein is produced using various expression systems, including wheat germ . This recombinant protein is used in research applications such as SDS-PAGE, ELISA, and Western Blotting (WB) . The recombinant protein is typically tag-free and is available in full-length form, making it suitable for various biochemical and biophysical studies .
The primary function of the ISOC2 protein is related to protein destabilization. This function is crucial for maintaining cellular homeostasis and regulating various cellular processes . The protein’s activity is influenced by its localization within the cell, primarily in the cytoplasm and nucleus .
Recombinant human ISOC2 protein is widely used in research to study its biochemical properties and functional roles. It is also used in assays to investigate protein-protein interactions, enzyme activity, and other cellular processes . The availability of high-quality recombinant protein allows researchers to conduct detailed studies on the protein’s structure and function.