IMPA1 Antibody
Description
Product Specs
Product Science Overview
Inositol monophosphatase 1 (IMPA1) is an enzyme encoded by the IMPA1 gene in humans . This enzyme plays a crucial role in the phosphatidylinositol signaling pathway, which is essential for various cellular processes, including cell growth, survival, and differentiation . IMPA1 is responsible for the dephosphorylation of inositol monophosphate to free inositol, a key step in the recycling of inositol for the synthesis of phosphatidylinositol and polyphosphoinositides .
IMPA1 is a ubiquitous enzyme with broad specificity and is found in various tissues, including the brain, where it is involved in the regulation of mood and cognitive functions . Mutations in the IMPA1 gene have been associated with intellectual disabilities and other neurological disorders .
Mouse anti-human IMPA1 antibody is a monoclonal antibody that specifically targets the human IMPA1 protein . This antibody is commonly used in research to study the expression and function of IMPA1 in various biological samples, including human, mouse, and rat tissues . The antibody is typically produced by immunizing mice with a synthetic peptide containing the human IMPA1 sequence, followed by hybridoma technology to generate monoclonal antibodies .
The mouse anti-human IMPA1 antibody is widely used in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to detect and quantify IMPA1 protein levels in different samples . It is also used in functional studies to investigate the role of IMPA1 in cellular processes and disease mechanisms .
The study of IMPA1 and its interactions using mouse anti-human IMPA1 antibodies has significant implications for understanding various biological processes and diseases. For instance, research on IMPA1 can provide insights into the molecular mechanisms underlying mood disorders, such as bipolar disorder, and contribute to the development of new therapeutic strategies .
Additionally, the use of mouse anti-human IMPA1 antibodies in research can help identify potential biomarkers for neurological disorders and other diseases, facilitating early diagnosis and treatment .
