FAM107B Human

Family with Sequence Similarity 107, Member B Human Recombinant
Cat. No.
BT7730
Source
Escherichia Coli.
Synonyms
FAM107B protein, FLJ45505, MGC11034, Protein FAM107B, Family with Sequence Similarity 107, Member B, FAM107B, C10orf45.
Appearance
Sterile filtered colorless solution.
Purity
Greater than 95% as determined by SDS-PAGE.
Usage

THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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Description

FAM107B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 154 amino acids (1-131) and having a molecular mass of 17.9kDa.
FAM107B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Product Specs

Introduction
Belonging to the FAM107 family, Family with Sequence Similarity 107, Member B (FAM107B) is found in most human tissues and is present throughout human development.
Description
FAM107B Human Recombinant protein is produced in E. coli. It is a single, non-glycosylated polypeptide chain containing 154 amino acids (residues 1-131) with a molecular weight of 17.9 kDa. A 23 amino acid His-tag is fused to the N-terminus. The protein is purified using proprietary chromatographic techniques.
Physical Appearance
A clear, colorless solution that is sterile filtered.
Formulation
The FAM107B solution has a concentration of 1mg/ml and contains 20mM Tris-HCl buffer with a pH of 8.0, 0.15M NaCl, 20% glycerol, and 1mM DTT.
Stability
For short-term storage (2-4 weeks), the product can be stored at 4°C. For extended storage, it is recommended to freeze the product at -20°C. The addition of a carrier protein (0.1% HSA or BSA) is advised for long-term storage. Repeated freezing and thawing should be avoided.
Purity
Purity is determined to be greater than 95% by SDS-PAGE analysis.
Synonyms
FAM107B protein, FLJ45505, MGC11034, Protein FAM107B, Family with Sequence Similarity 107, Member B, FAM107B, C10orf45.
Source
Escherichia Coli.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAEPDYI EDDNPELIRP QKLINPVKTS RNHQDLHREL LMNQKRGLAP QNKPELQKVM EKRKRDQVIK QKEEEAQKKK SDLEIELLKR QQKLEQLELE KQKLQEEQEN APEFVKVKGN LRRTGQEVAQ AQES.

Product Science Overview

Gene and Protein Structure

FAM107B is located on chromosome 10 and is also known by other names such as C10orf45, FLJ45505, and HITS . The gene encodes a protein that consists of 154 amino acids and has a molecular mass of approximately 17.9 kDa . The recombinant form of FAM107B is produced in Escherichia coli (E. coli) and is a single, non-glycosylated polypeptide chain . It is often fused to a 23 amino acid His-tag at the N-terminus to facilitate purification through chromatographic techniques .

Biological Function

FAM107B is predicted to play a role in the sensory perception of sound . It is involved in various cellular processes, including cell proliferation, immune response, and protein ubiquitination . The protein is expressed in multiple tissues, including lymphoid tissue, bone marrow, testis, skeletal muscle, and various immune cells .

Disease Associations

Mutations or dysregulation of FAM107B have been linked to several diseases. Notably, it is associated with tibial neuropathy and cataract 13 with adult I phenotype . These associations highlight the potential clinical significance of FAM107B and its importance in maintaining normal physiological functions.

Research and Applications

The recombinant form of FAM107B is valuable in research settings. It allows scientists to study the protein’s function, interactions, and role in disease mechanisms. The availability of recombinant FAM107B facilitates various experimental approaches, including structural analysis, functional assays, and therapeutic research.

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