CTSE Mouse
Sf9, Insect cells.
CTSE, A430072003Rik, C920004C08Rik, CatE, CE.
Greater than 95.0% as determined by SDS-PAGE.
Description
CTSE Mouse produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 385 amino acids ( 21-397 a.a.) and having a molecular mass of 41.8 kDa.
CTSE is expressed with a 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Product Specs
CTSE, A430072003Rik, C920004C08Rik, CatE, CE.
Sf9, Insect cells.
ALHRVPLRRH QSLRKKLRAQ GQLSEFWRSH NLDMTRLSES CNVYSSVNEP LINYLDMEYF GTISIGTPPQ NFTVIFDTGS SNLWVPSVYC TSPACKAHPV FHPSQSDTYT EVGNHFSIQY GTGSLTGIIG ADQVSVEGLT VDGQQFGESV KEPGQTFVNA EFDGILGLGY PSLAAGGVTP VFDNMMAQNL VALPMFSVYL SSDPQGGSGS ELTFGGYDPS HFSGSLNWIP VTKQAYWQIA
LDGIQVGDTV MFCSEGCQAI VDTGTSLITG PPDKIKQLQE AIGATPIDGE YAVDCATLDT MPNVTFLINE VSYTLNPTDY ILPDLVEGMQ FCGSGFQGLD IPPPAGPLWI LGDVFIRQFY SVFDRGNNQV GLAPAVPLEH HHHHH.
Product Science Overview
Recombinant Mouse Cathepsin E is produced using a mouse myeloma cell line, NS0-derived mouse Cathepsin E protein (Gln19-Pro397), with a C-terminal 10-His tag . The recombinant protein is supplied as a 0.2 μm filtered solution in MES and NaCl, and it is recommended to store it at -20 to -70 °C to maintain stability .
Recombinant Mouse Cathepsin E is used in various research applications, including studies on antigen processing and presentation, as well as in the investigation of its role in the immune system . It is also utilized in assays to measure its ability to cleave specific fluorogenic peptide substrates .
The study of Cathepsin E is significant due to its role in the immune system. It has been implicated in antigen processing within dendritic cells, which are key antigen-presenting cells in the immune system . Understanding the function and regulation of Cathepsin E can provide insights into immune responses and potential therapeutic targets for immune-related diseases.
