Collagen-VI Bovine
Bovine placenta.
Filtered White lyophilized (freeze-dried) powder.
> 90.0%.
Description
Bovine Collagen-VI is a natural protein purified from Bovine placenta. Bovine Collagen-VI is purified by proprietary chromatographic techniques.
Product Specs
Collagen is a fibrous protein crucial for tissue strength and integrity within the extracellular matrix. Collagen and gelatin, derived from collagen, have widespread applications in various industries. While animal-sourced collagen is readily available and cost-effective, it can pose risks such as inflammatory reactions and potential contamination. The variability in animal collagen extraction and processing further complicates its use. Recombinant collagens offer a safer and more consistent alternative, closely resembling native collagen and minimizing potential health risks.
Bovine Collagen-VI is a naturally occurring protein extracted from bovine placenta and purified using specialized chromatographic methods.
It appears as a white, freeze-dried powder that has been filtered.
The lyophilization process of Collagen-VI excludes any additional additives.
To create a working stock solution of at least 100 µg/ml, reconstitute the lyophilized powder with 0.5 M acetic acid at a pH of 2.5. This solution can be diluted further with aqueous solutions as needed.
While the lyophilized form of Collagen-VI remains stable at room temperature for up to 3 weeks, it is recommended to store it in a dry environment below -18°C. After reconstitution, Collagen-VI can be stored at 4°C for 2 to 7 days. For extended storage, freezing below -18°C is advised. To preserve its integrity, the addition of a carrier protein like 0.1% HSA or BSA is recommended for long-term storage. Avoid repeated freeze-thaw cycles.
Greater than 90.0% pure.
Bovine placenta.
Product Science Overview
Bovine Collagen Type VI is derived from cows, specifically from the hide, bones, and tendons. The extraction process involves mechanical separation and salt precipitation to purify the collagen while maintaining its native structure . This type of collagen is often used in various applications, including nutritional supplements and biomedical research.
Collagen Type VI plays a significant role in maintaining the structural integrity of tissues. It is a major component of the endomysium, which is the connective tissue surrounding muscle fibers. In muscle tissue, collagen constitutes about 1-2% of the tissue and accounts for approximately 6% of the weight of strong, tendinous muscles .
This collagen type is also involved in cell adhesion, migration, and tissue repair. It interacts with other extracellular matrix components, contributing to the overall stability and function of tissues.
Bovine Collagen Type VI has several applications:
- Biomedical Research: It is used as a control or standard in various immunological assays, such as ELISA and immunoprecipitation .
- Nutritional Supplements: Bovine collagen supplements are popular for their potential health benefits, including improved skin health, joint support, and gut health .
- Cosmetics: Due to its skin-rejuvenating properties, bovine collagen is often included in skincare products to enhance skin elasticity and reduce wrinkles .
Bovine collagen, including Type VI, is known for its potential health benefits:
- Skin Health: It helps in maintaining skin elasticity and hydration, reducing the appearance of wrinkles .
- Joint Support: Collagen supplements can support joint health by providing the necessary building blocks for cartilage repair .
- Gut Health: Collagen may help in maintaining the integrity of the gut lining, which is essential for overall digestive health .
