Escherichia Coli.
Sterile Filtered colorless liquid formulation.
Greater than 90.0% as determined by SDS-PAGE.
Recombinant Human Creatine Kinase MB produced in E.Coli is a single, non-glycosylated, polypeptide chain, having a molecular weight of ~44kDa.
The CKMB is purified by proprietary chromatographic techniques.
Creatine Kinase (CK) exists in three primary forms (isoenzymes): MM, MB, and BB, distributed in various tissues such as muscle, heart, and brain. Recombinant CK proteins are valuable tools for calibrating diagnostic equipment and investigating neuromuscular diseases. Their applications extend to studying conditions like heart disease, mitochondrial disorders, inflammatory myopathies, myasthenia gravis, polymyositis, McArdle's disease, neuromuscular junction disorders, muscular dystrophy, amyotrophic lateral sclerosis (ALS), thyroid disorders, central core disease, acid maltase deficiency, myoglobinuria, rhabdomyolysis, motor neuron diseases, rheumatic diseases, and other conditions associated with abnormal CK levels.
Recombinant Human Creatine Kinase MB, expressed in E. coli, is a single, non-glycosylated polypeptide chain with a molecular weight of approximately 44 kDa. The purification of CKMB is achieved using proprietary chromatographic techniques.
Sterile Filtered colorless liquid.
The protein is supplied in a solution containing 50% glycerol.
CKMB, while stable at 10°C for up to 7 days, should be stored at or below -18°C. Avoid repeated freeze-thaw cycles.
Purity is determined to be greater than 90.0% using SDS-PAGE analysis.
Escherichia Coli.