CCDC43 Human
Description
Product Specs
Product Science Overview
The CCDC43 gene is located on chromosome 17 and is a protein-coding gene . The coiled-coil domain is a highly conserved superhelical protein motif, which plays a crucial role in the structural integrity and function of the protein . The CCDC43 protein is involved in various cellular processes due to its ability to form stable, elongated structures that facilitate protein-protein interactions .
CCDC43, like other coiled-coil domain-containing proteins, has been implicated in a variety of physiological and pathological processes . These proteins are known to interact with molecular components of signaling pathways and determine physiological functions at the cellular and organ levels . Some of the key functions include:
- Gametogenesis: CCDC proteins play a role in the development and maturation of gametes .
- Embryonic Development: They are involved in the early stages of embryonic development, ensuring proper cell differentiation and growth .
- Hematopoiesis: CCDC proteins contribute to the formation and development of blood cells .
- Angiogenesis: They are involved in the formation of new blood vessels from pre-existing ones .
- Ciliary Development: CCDC proteins are essential for the formation and function of cilia, which are hair-like structures on the surface of cells .
Mutations or dysregulation of CCDC43 and other coiled-coil domain-containing proteins have been associated with various diseases, including cancers . Polymorphisms in CCDC genes are linked to an increased risk of lifetime diseases . Due to their involvement in many biological processes, CCDC proteins are extensively studied for their potential roles in disease mechanisms and therapeutic targets .
Research on CCDC43 and other coiled-coil domain-containing proteins continues to be an active area of investigation . Understanding the functional roles and regulatory mechanisms of these proteins can provide insights into their contributions to health and disease. Additionally, recombinant forms of these proteins, such as human recombinant CCDC43, are used in various research applications to study their structure, function, and interactions.
