Antide

Antide Acetate has the molecular formula C82H108ClN17O14 and a molecular weight of 1591.32 g/mol . It is a complex peptide with a specific sequence of amino acids, including modified residues that enhance its stability and activity. The peptide is typically supplied as a white solid and is soluble in water and other aqueous solutions .

As a GnRH antagonist, Antide Acetate works by binding to GnRH receptors in the pituitary gland, thereby inhibiting the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This suppression of LH and FSH leads to a decrease in the production of sex hormones such as testosterone and estrogen . This mechanism is particularly useful in conditions where hormone regulation is crucial, such as in the treatment of hormone-sensitive cancers.

1. Cancer Research: Antide Acetate is used in the study of hormone-dependent cancers, such as prostate cancer. By inhibiting the production of testosterone, it helps in understanding the role of androgens in cancer progression and in developing potential therapeutic strategies .

2. Endometriosis: The peptide is also explored for its potential in treating endometriosis, a condition characterized by the growth of endometrial tissue outside the uterus. By reducing estrogen levels, Antide Acetate may help in managing the symptoms and progression of this condition .

3. Contraceptive Research: Due to its ability to suppress reproductive hormones, Antide Acetate is studied for its potential use in male contraception. By inhibiting the production of testosterone and spermatogenesis, it offers a reversible method of contraception .

Antide Acetate is typically handled in research laboratories under controlled conditions. It is stored at 2-8°C for short-term use and at -20°C for long-term storage to maintain its stability and activity . Safety data sheets (SDS) are provided with the product to ensure proper handling and to address any potential hazards .