ACY3 Human
Aspartoacylase-2, Acylase III, Aminoacylase-3, ACY-3, Hepatitis C virus core-binding protein 1, HCBP1, ACY3, ASPA2.
Description
ACY3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 342 amino acids (1-319 a.a.) and having a molecular mass of 37.6kDa.
ACY3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Specs
Aspartoacylase-2, Acylase III, Aminoacylase-3, ACY-3, Hepatitis C virus core-binding protein 1, HCBP1, ACY3, ASPA2.
MGSSHHHHHH SSGLVPRGSH MGSMCSLPVP REPLRRVAVT GGTHGNEMSG VYLARHWLHA PAELQRASFS AVPVLANPAA TSGCRRYVDHDLNRTFTSSF LNSRPTPDDP YEVTRARELN QLLGPKASGQ AFDFVLDLHN TTANMGTCLI AKSSHEVFAM HLCRHLQLQY PELSCQVFLY QRSGEESYNL DSVAKNGLGL ELGPQPQGVL RADIFSRMRT LVATVLDFIE LFNQGTAFPA FEMEAYRPVG VVDFPRTEAG HLAGTVHPQL QDRDFQPLQP GAPIFQMFSG EDLLYEGEST VYPVFINEAA YYEKGVAFVQ TEKFTFTVPA MPALTPAPSP AS.
Product Science Overview
ACY3 is primarily located in the cytoplasm of S2 and S3 proximal tubules and the apical domain of S1 proximal tubules in the kidney . It is also expressed at low levels in other tissues such as the stomach, testis, heart, brain, lung, and liver . The enzyme may function as a core binding protein for the Hepatitis C virus (HCV) .
Recombinant human ACY3 is produced using an Escherichia coli (E. coli) expression system . The recombinant protein typically includes a 6His tag at the N-terminus to facilitate purification and detection . The full-length protein ranges from amino acids 1 to 319 and has a molecular weight of approximately 35 kDa under reducing conditions . The protein is supplied in a buffer solution containing Tris-HCl, NaCl, DTT, and glycerol, and is stable for several months when stored at -70°C .
