ABRACL Human

• Gene Name: ABRACL (ABRA C-Terminal Like)
• Synonyms: Costars, HSPC280, PRO2013, C6orf115
• Chromosome Location: 6q24.1
• Protein Length: 104 amino acids
• Molecular Mass: 11.4 kDa

The recombinant human ABRACL protein is typically expressed in Escherichia coli (E. coli) and purified using conventional chromatography techniques. The protein is often fused to a His-tag at the N-terminus to facilitate purification .

ABRACL is predicted to be involved in the regulation of actin filament-based processes, which are crucial for various cellular functions, including cell shape, motility, and division . The protein’s specific role in these processes is still under investigation, but its involvement in actin regulation suggests it may play a significant role in maintaining cellular structure and dynamics.

The expression patterns of ABRACL across different tissues are not fully characterized. However, as a member of the Costars family, it is likely to be expressed in various eukaryotic tissues, excluding fungi .

The regulatory mechanisms governing ABRACL expression and function are not well understood. Further research is needed to elucidate the transcriptional and post-transcriptional regulation of this protein.

Recombinant ABRACL protein is used in various research applications to study its function and role in actin filament regulation. It is also utilized in structural biology studies to understand its interaction with other proteins and cellular components.

Recombinant ABRACL protein can be stored at +4°C for short-term use (1-2 weeks). For long-term storage, it should be aliquoted and stored at -20°C or -70°C to avoid repeated freeze-thaw cycles .